early conceptus |
embryo ectoderm |
embryo endoderm |
embryo mesoderm |
embryo mesenchyme |
extraembryonic component |
alimentary system |
auditory system |
branchial arches |
cardiovascular system |
connective tissue |
endocrine system |
exocrine system |
hemolymphoid system |
integumental system |
limbs |
liver and biliary system |
musculoskeletal system |
nervous system |
olfactory system |
reproductive system |
respiratory system |
urinary system |
visual system |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription Start Site | Location | Distance from Gene 5'-end |
Tssr57727 | Chr6:91660575-91660625 (+) | -431 bp |
Tssr57728 | Chr6:91661042-91661113 (+) | 47 bp |
Tssr57729 | Chr6:91661158-91661172 (+) | 134 bp |
Tssr57730 | Chr6:91667374-91667421 (+) | 6,367 bp |
Tssr57731 | Chr6:91676090-91676102 (+) | 15,065 bp |
Tssr57732 | Chr6:91676119-91676136 (+) | 15,097 bp |
Tssr57733 | Chr6:91678630-91678643 (+) | 17,606 bp |
Tssr57734 | Chr6:91682785-91682813 (+) | 21,768 bp |
Tssr57735 | Chr6:91682831-91682860 (+) | 21,815 bp |
Tssr57737 | Chr6:91698699-91698721 (+) | 37,679 bp |
Tssr57738 | Chr6:91701911-91701925 (+) | 40,887 bp |
Tssr57739 | Chr6:91703053-91703069 (+) | 42,030 bp |
Tssr57740 | Chr6:91703091-91703113 (+) | 42,071 bp |
Tssr57741 | Chr6:91703165-91703187 (+) | 42,145 bp |
Tssr57742 | Chr6:91703188-91703210 (+) | 42,168 bp |
Tssr57743 | Chr6:91711835-91711841 (+) | 50,807 bp |
Tssr57744 | Chr6:91716151-91716162 (+) | 55,126 bp |
Tssr57745 | Chr6:91716208-91716212 (+) | 55,179 bp |
Tssr57746 | Chr6:91731950-91731961 (+) | 70,925 bp |
Tssr57747 | Chr6:91732139-91732155 (+) | 71,116 bp |
Tssr57748 | Chr6:91732978-91732998 (+) | 71,957 bp |
Tssr57749 | Chr6:91733124-91733138 (+) | 72,100 bp |
Tssr57750 | Chr6:91733474-91733501 (+) | 72,457 bp |
Tssr57751 | Chr6:91733575-91733605 (+) | 72,559 bp |
Tssr57752 | Chr6:91733964-91733975 (+) | 72,939 bp |
Tssr1939 | Chr6:91734098-91734103 (+) | 73,070 bp |
Tssr57753 | Chr6:91734800-91734810 (+) | 73,774 bp |
Tssr57754 | Chr6:91734899-91734906 (+) | 73,872 bp |
Tssr57755 | Chr6:91734990-91735002 (+) | 73,965 bp |
Tssr57756 | Chr6:91735023-91735042 (+) | 74,002 bp |
Tssr57757 | Chr6:91735060-91735067 (+) | 74,033 bp |
Tssr57758 | Chr6:91735091-91735103 (+) | 74,066 bp |
Tssr57759 | Chr6:91735316-91735327 (+) | 74,291 bp |
Tssr57760 | Chr6:91735372-91735383 (+) | 74,347 bp |
Tssr57761 | Chr6:91735389-91735400 (+) | 74,364 bp |
Tssr57762 | Chr6:91735417-91735441 (+) | 74,398 bp |
Tssr57763 | Chr6:91735444-91735465 (+) | 74,424 bp |
Tssr57764 | Chr6:91735469-91735489 (+) | 74,448 bp |
Tssr57765 | Chr6:91735509-91735522 (+) | 74,485 bp |
Tssr57766 | Chr6:91735531-91735548 (+) | 74,509 bp |
Tssr57767 | Chr6:91735598-91735619 (+) | 74,578 bp |
Tssr57768 | Chr6:91735621-91735629 (+) | 74,594 bp |
Tssr57769 | Chr6:91735813-91735829 (+) | 74,790 bp |
Tssr57770 | Chr6:91735920-91735940 (+) | 74,899 bp |
QTL | Genetic Location* | Genome Location (GRCm39) | Reference | QTL Note |
Cia3 | Chr6, 52.75 cM | Chr6:113324286-113324483 | J:81372 | Microarray gene expression analysis was used to identify candidate genes for QTLs associated with collagen-induced arthritis. RNA from inflamed paws of collagen-treated mice were used in the microarray analysis and compared to RNA from normal paws. 223 genes showed a four-fold or greater expression difference between inflamed and normal paws. Nine of these genes are located near previously identified arthritis severity/susceptibility QTLs and may be considered for candidates. For Cia1 on mouse Chromosome 17 (18.6 cM near the H2 locus) differential expression was observed for H2-Eb1 (18.66 cM) and H2-T23 (19.73 cM). For Cia2 and Cia4 on mouse Chromosome 2 (both are located at 34 cM) differential expression was observed for Fap (36 cM) and Gcg (36 cM). For Cia3 (48.7 cM) and Cia6 (30 cM) on mouse Chromosome 6 differential expression was observed for Raf1 (52.5 cM) and Slc6a6 (38.2 cM), respectively. For Cia5 (40 cM) on mouse Chromosome 4 differential expression was observed for Ctsk (47.9 cM) and Cd53(50.5 cM). For Cia8 (40.4 cM) on mouse Chromosome 10 differential expression was observed for Bsg (42.4 cM). |
Cia6 | Chr6, 32.53 cM | Chr6:4464884-87403016 | J:81372 | Microarray gene expression analysis was used to identify candidate genes for QTLs associated with collagen-induced arthritis. RNA from inflamed paws of collagen-treated mice were used in the microarray analysis and compared to RNA from normal paws. 223 genes showed a four-fold or greater expression difference between inflamed and normal paws. Nine of these genes are located near previously identified arthritis severity/susceptibility QTLs and may be considered for candidates. For Cia1 on mouse Chromosome 17 (18.6 cM near the H2 locus) differential expression was observed for H2-Eb1 (18.66 cM) and H2-T23 (19.73 cM). For Cia2 and Cia4 on mouse Chromosome 2 (both are located at 34 cM) differential expression was observed for Fap (36 cM) and Gcg (36 cM). For Cia3 (48.7 cM) and Cia6 (30 cM) on mouse Chromosome 6 differential expression was observed for Raf1 (52.5 cM) and Slc6a6 (38.2 cM), respectively. For Cia5 (40 cM) on mouse Chromosome 4 differential expression was observed for Ctsk (47.9 cM) and Cd53(50.5 cM). For Cia8 (40.4 cM) on mouse Chromosome 10 differential expression was observed for Bsg (42.4 cM). |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/15/2024 MGI 6.24 |
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