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Trdc Gene Detail
Summary
  • Symbol
    Trdc
  • Name
    T cell receptor delta, constant region
  • Synonyms
    Tcrd-C
Location &
Maps
more
  • Sequence Map
    Chr14:54380308-54383565 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 27.66 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    71 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98612
gene segment Chr14:54380308-54386325 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002421
gene segment Chr14:48069781-48075730 (+)
A/J MGP_AJ_G0002396
gene segment Chr14:47163137-47169097 (+)
AKR/J MGP_AKRJ_G0002382
gene segment Chr14:48869392-48875327 (+)
BALB/cJ MGP_BALBcJ_G0002391
gene segment Chr14:47128081-47134023 (+)
C3H/HeJ MGP_C3HHeJ_G0002369
gene segment Chr14:48551476-48557586 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002517
gene segment Chr14:50534499-50540461 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002119
gene segment Chr14:45576153-45582129 (+)
CAST/EiJ MGP_CASTEiJ_G0002331
gene segment Chr14:44783357-44790463 (+)
CBA/J MGP_CBAJ_G0002361
gene segment Chr14:52025687-52033561 (+)
DBA/2J MGP_DBA2J_G0002367
gene segment Chr14:46900757-46907440 (+)
FVB/NJ MGP_FVBNJ_G0002379
gene segment Chr14:46361892-46367854 (+)
LP/J MGP_LPJ_G0002421
gene segment Chr14:49095340-49101275 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002349
gene segment Chr14:51469786-51476828 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002511
gene segment Chr14:48053307-48059295 (+)
PWK/PhJ MGP_PWKPhJ_G0002292
gene segment Chr14:43429606-43435833 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002245
gene segment Chr14:44027347-44035547 (+)
WSB/EiJ MGP_WSBEiJ_G0002361
gene segment Chr14:48343199-48349507 (+)



Homology
more
  • Human Ortholog
    TRDC, T cell receptor delta constant
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRDC, T cell receptor delta constant
  • Synonyms
    TCRD
  • Links
    NCBI Gene ID: 28526
    UniProt: B7Z8K6

  • Chr Location
    14q11.2; chr14:22462932-22466577 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from multigenic genotypes
    39 phenotype references
Mice homozygous for a reporter allele are viable, healthy, and exhibit normal T cell development.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 100123473 NCBI Gene Model | MGI Sequence Detail 3258 C57BL/6J ±  kb
polypeptide A0A0G2JEU3 UniProt | EBI | MGI Sequence Detail 153 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR003597 Immunoglobulin C1-set
    IPR051755 Immunoglobulin-like Cell Surface Receptor
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
Molecular
Reagents
less
  • All nucleic 13
    Genomic 5
    cDNA 5
    Other 3
Other
Accession IDs
less
MGD-MRK-14904
References
more
  • Summaries
    All 56
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 39
  • Earliest
    J:31196 Malissen M, et al., A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition. Cell. 1988 Oct 7;55(1):49-59
  • Latest
    J:350590 Liu T, et al., An axon-T cell feedback loop enhances inflammation and axon degeneration. Cell Rep. 2024 Feb 27;43(2):113721

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory