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Ugt2b5 Gene Detail
Summary
  • Symbol
    Ugt2b5
  • Name
    UDP glucuronosyltransferase 2 family, polypeptide B5
  • Synonyms
    m-1, Udpgt-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:98900
    NCBI Gene: 22238
  • Member of
    Ugt2 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:87272819-87288177 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    429 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98900
 protein coding gene Chr5:87272805-87288199 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029679
 protein coding gene Chr5:88001928-88027443 (-)
A/J no annotation
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0029657
 protein coding gene Chr5:85428193-85441175 (-)
C3H/HeJ MGP_C3HHeJ_G0029379
 protein coding gene Chr5:87657737-87674311 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030111
 protein coding gene Chr5:91625951-91647602 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027350
 protein coding gene Chr5:80121206-80135280 (-)
CAST/EiJ MGP_CASTEiJ_G0028788
 protein coding gene Chr5:87018412-87036318 (-)
CBA/J MGP_CBAJ_G0029349
 protein coding gene Chr5:94666144-94678757 (-)
DBA/2J MGP_DBA2J_G0029492
 protein coding gene Chr5:84585170-84710681 (-)
FVB/NJ MGP_FVBNJ_G0029454
 protein coding gene Chr5:83511304-83528937 (-)
LP/J MGP_LPJ_G0029580
 protein coding gene Chr5:88425517-88445801 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0030143
 protein coding gene Chr5:86742811-86765646 (-)
PWK/PhJ MGP_PWKPhJ_G0028510
 protein coding gene Chr5:83596760-83623343 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028346
 protein coding gene Chr5:86288536-86304906 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    UGT2B28, UDP glucuronosyltransferase family 2 member B28
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGT2B28, UDP glucuronosyltransferase family 2 member B28
  • Links
    NCBI Gene ID: 54490
    neXtProt AC: NX_Q9BY64
    UniProt: Q9BY64

  • Chr Location
    4q13.2; chr4:69280475-69295050 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    44
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000054630 Ensembl Gene Model | MGI Sequence Detail 15359 C57BL/6J ±  kb
transcript ENSMUST00000067790 Ensembl | MGI Sequence Detail 1858 Not Applicable  
polypeptide ENSMUSP00000068282 Ensembl | MGI Sequence Detail 530 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000017225 UDP-glucuronosyltransferase 2B5
    (term hierarchy)
  • EC
    2.4.1.17
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR050271 UDP-glycosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
  • GlyGen
    P17717 4 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15341, MGD-MRK-15347, MGI:2140808
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory