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Ifi47 Gene Detail
Summary
  • Symbol
    Ifi47
  • Name
    interferon gamma inducible protein 47
  • Synonyms
    47kDa, Igrd, Iigp4, IRG-47
  • Feature Type
    protein coding gene
  • IDs
    MGI:99448
    NCBI Gene: 15953
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:48967414-48987801 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 29.08 cM, cytoband B1.2
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_99448
 protein coding gene Chr11:48967414-48987814 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018216
 protein coding gene Chr11:48140936-48152214 (+)
A/J MGP_AJ_G0018186
 protein coding gene Chr11:46280270-46300566 (+)
AKR/J MGP_AKRJ_G0018153
 protein coding gene Chr11:47727138-47745649 (+)
BALB/cJ MGP_BALBcJ_G0018155
 protein coding gene Chr11:46532308-46552847 (+)
C3H/HeJ MGP_C3HHeJ_G0017969
 protein coding gene Chr11:47750343-47773667 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018606
 protein coding gene Chr11:49583763-49605559 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016261
 protein coding gene Chr11:43999102-44009293 (+)
CAST/EiJ MGP_CASTEiJ_G0017532
 protein coding gene Chr11:47809693-47823404 (+)
CBA/J MGP_CBAJ_G0017941
 protein coding gene Chr11:51894546-51918723 (+)
DBA/2J MGP_DBA2J_G0018050
 protein coding gene Chr11:46138542-46158536 (+)
FVB/NJ MGP_FVBNJ_G0018045
 protein coding gene Chr11:45732853-45753023 (+)
LP/J MGP_LPJ_G0018124
 protein coding gene Chr11:48464914-48475026 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018069
 protein coding gene Chr11:53413451-53434412 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018644
 protein coding gene Chr11:47654365-47876584 (+)
PWK/PhJ MGP_PWKPhJ_G0017311
 protein coding gene Chr11:46476551-46487427 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017105
 protein coding gene Chr11:47543811-47554980 (+)
WSB/EiJ MGP_WSBEiJ_G0017583
 protein coding gene Chr11:47518710-47528885 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
In the absence of infection, mice show no overt phenotype. Resistance to protozoan parasitic infection is impaired in homozygous mutant mice, whereas resistance to bacterial and viral infection are normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    826
  • Tissues
    97
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000078920 Ensembl Gene Model | MGI Sequence Detail 20388 C57BL/6J ±  kb
transcript ENSMUST00000109202 Ensembl | MGI Sequence Detail 1773 Not Applicable  
polypeptide ENSMUSP00000104825 Ensembl | MGI Sequence Detail 420 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • InterPro Domains
    IPR051515 Immunity-related GTPase
    IPR007743 Immunity-related GTPases-like
    IPR030385 IRG-type guanine nucleotide-binding (G) domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
less
  • All nucleic 10
    Genomic 1
    cDNA 8
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-16217
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 9
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:307941 Zuo B, et al., Analysis of microsatellite polymorphism in inbred knockout mice. PLoS One. 2012;7(4):e34555
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory