A^iy
Spontaneous Allele Detail

Summary

• Symbol: A^iy
• Name: nonagouti; intermediate yellow
• MGI ID: MGI:1855933
• Gene: a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: A^iy page

Mutation origin

• Strain of Origin: C3H/HeJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: This allele is the result of a 1 kb intracisternal A particle (IAP) transposon insertion. Genomic Southern hybridization analysis places the insertion just upstream of exon 2. (J:19977)
• Inheritance: Dominant

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any a Mutation: 463 strains or lines available

Notes

The A^vy allele arose spontaneously in the C3H/HeJ strain. Heterozygotes (A^iy/a) are sootier than A^y/a and are often indistinguishable from A/a. They do not have the mottling often observed in A^vy/a. Homozygotes are viable, as are A^vy/A^y and A^iy/A^vy (J:13441).

Genbank ID for this mutation: S74469

References

• Original: J:13441 Dickie MM, Intermediate yellow. Mouse News Lett. 1966;34:30
• All: 6 reference(s)