a^t
Spontaneous Allele Detail

Summary

• Symbol: a^t
• Name: nonagouti; black and tan
• MGI ID: MGI:1855941
• Gene: a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: a^t page

a^t/a^t

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: English fancy stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This allele comprises a 6 kb insertion containing a retrovirus-like transposable element VL30 and a single 526 bp repeat into the first intron of the agouti gene at the same position as for alleles a and A^w. (J:16984)
• Inheritance: Other (see notes)

Expression

In Mice Carrying this Mutation:

2 assay results

Tumor Data

List all tumor models in MMHCdb carrying a^t

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 9 strains available Cell Lines: 0 lines available
• Carrying any a Mutation: 463 strains or lines available

Notes

This allele is recessive to A and A^w on the dorsum and dominant to all agouti alleles on the ventrum except for A^w from which it is indistinguishable (J:78801) .

References

• Original: J:15011 Dunn LC, A Fifth Allelomorph in the Agouti Series of the House Mouse. Proc Natl Acad Sci U S A. 1928 Oct;14(10):816-9
• All: 20 reference(s)