a^16H
Chemically induced Allele Detail

Summary

• Symbol: a^16H
• Name: nonagouti; nonagouti 16 Harwell
• MGI ID: MGI:1855950
• Gene: a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: a^16H page

a^16H/a^l

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: Sequence analysis showed this allele comprises a T to C transition in the agouti coding region. Northern analysis of mRNA from skin of homozygotes showed levels 70% of wild-type. (J:17867, J:24934)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any a Mutation: 463 strains or lines available

Notes

As a^16H/A^y and a^16H/a^l mice are viable, the lethal site of a^16H must differ from that of the other two lethal alleles. a^16H/a mice resemble A/A on the belly and flanks and a/a on the back. (Lyon MF 1985).

References

• Original: J:8093 Lyon MF, et al., A recessive allele of the mouse agouti locus showing lethality with yellow, Ay. Genet Res. 1985 Aug;46(1):95-9
• All: 6 reference(s)