Pcdh15^av-J
Spontaneous Allele Detail

Summary

• Symbol: Pcdh15^av-J
• Name: protocadherin 15; Ames waltzer Jackson
• MGI ID: MGI:1855958
• Synonyms: av^J
• Gene: Pcdh15 Location: Chr10:72935174-74485569 bp, + strand Genetic Position: Chr10, 37.43 cM
• Alliance: Pcdh15^av-J page

Mutation origin

• Strain of Origin: C57BLKS/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The mutation is a 834 bp deletion that is predicted to delete 278 amino acids from the extracellular domain of the encoded protein. (J:66738)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pcdh15 Mutation: 135 strains or lines available

Notes

Several remutations to Pcdh15 have occurred in stocks at The Jackson Laboratory. All show the characteristic head-tossing, circling, and deafness (J:28688).

References

• Original: J:28688 Cook S, et al., Re-mutation to Ames waltzer. Mouse Genome. 1993;91:554
• All: 8 reference(s)