Kcnn2^bc-3J
Spontaneous Allele Detail

Summary

• Symbol: Kcnn2^bc-3J
• Name: potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; bouncy 3 Jackson
• MGI ID: MGI:1855967
• Gene: Kcnn2 Location: Chr18:45401927-45818950 bp, + strand Genetic Position: Chr18, 24.34 cM, cytoband C
• Alliance: Kcnn2^bc-3J page

Mutation origin

• Strain of Origin: C3H/HeSn

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A point mutation at coding nucleotide 599/1394/1424 of the transcript (NM_080465/ENSMUST00000066890/NM_001312905) is predicted to result in premature truncation at tryptophan 200/465/475 of the encoded protein (NP_536713:p.W200*, ENSMUSP00000067884:p.W465*, NP_001299834:p.W475*). (J:222308)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kcnn2 Mutation: 43 strains or lines available

References

• Original: J:6710 Lane PW, et al., Chromosome 18 of the house mouse. J Hered. 1981 Nov-Dec;72(6):409-12
• All: 3 reference(s)