Lyst^bg-2J
Spontaneous Allele Detail

Summary

• Symbol: Lyst^bg-2J
• Name: lysosomal trafficking regulator; beige 2 Jackson
• MGI ID: MGI:1855970
• Gene: Lyst Location: Chr13:13764982-13953388 bp, + strand Genetic Position: Chr13, 5.28 cM
• Alliance: Lyst^bg-2J page

Mutation origin

• Strain of Origin: Yellow stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This allele was identified by a noncomplementation test with Lyst^bg. Quantitative reverse transcription showed the molecular fault in the Lyst^bg-2J mutation may be an intronic retrotransposition event causing a five-fold decrease in transcription and mRNA instability. (J:34205)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Lyst Mutation: 225 strains or lines available

References

• Original: J:65327 Lane PW, bg-beige and bg^2J - beige-2J. Mouse News Lett. 1962;26:35
• All: 5 reference(s)