Gdf5^bp
Spontaneous Allele Detail

Summary

• Symbol: Gdf5^bp
• Name: growth differentiation factor 5; brachypodism
• MGI ID: MGI:1855972
• Gene: Gdf5 Location: Chr2:155782943-155787204 bp, - strand Genetic Position: Chr2, 77.26 cM
• Alliance: Gdf5^bp page

Mutation origin

• Strain of Origin: Swiss albino stock

Mutation description

• Allele Type: Spontaneous
• Mutations: Intragenic deletion, Inversion
• Mutation details: This mutation involves deletion of some bases, and inversion of others, in the coding sequence. Specifically, bases 477-483 of the wild-type ORF are deleted, followed by an inversion of bases 484-496. The resulting frameshift creates a translational stop codon 62 amino acids later. (J:17582)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	10 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Gdf5 Mutation: 32 strains or lines available

References

• Original: J:19596 Landauer W, Brachypodism - A recessive mutation of house-mice. J Hered. 1952;43(6):293-8
• All: 8 reference(s)