Myo5a^d
Spontaneous Allele Detail

Summary

• Symbol: Myo5a^d
• Name: myosin VA; dilute
• MGI ID: MGI:1856004
• Synonyms: blue dilution, d, d^v, Maltese dilution
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^d page

A homozygous a/a Myo5a^d/ Myo5a^d mouse with wild-type nonagouti black sibling

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: old mutant of the mouse fancy

Mutation description

• Allele Type: Spontaneous
• Mutation: Viral insertion
• Mutation details: This mutation is the result of the integration of ecotropic murine leukemia virus Emv-3 into a noncoding region of the Myo5a^d gene. Reversions of Myo5a^d to wild-type are caused by excision of the virus leaving exactly one long terminal repeat in place. (J:6587, J:7092, J:7751)
• Inheritance: Recessive

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Myo5a^d

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 105 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 265 strains or lines available

References

• Original: J:12958 Russell ES, A Quantitative Histological Study of the Pigment Found in the Coat-Color Mutants of the House Mouse. IV. the Nature of the Effects of Genic Substitution in Five Major Allelic Series. Genetics. 1949 Mar;34(2):146-66
• All: 38 reference(s)