Myo5a^d-l
Spontaneous Allele Detail

Summary

• Symbol: Myo5a^d-l
• Name: myosin VA; dilute lethal
• MGI ID: MGI:1856005
• Synonyms: d^l
• Gene: Myo5a Location: Chr9:74978297-75130970 bp, + strand Genetic Position: Chr9, 42.26 cM
• Alliance: Myo5a^d-l page

Mutation origin

• Strain of Origin: C57BL/Gr

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• This Myo5a allele was identifed by a noncomlementation test result with Myo5a^d. (J:12978)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Myo5a Mutation: 265 strains or lines available

Notes

Myo5a^d-l, dilute-lethal, recessive. Dilute-lethal arose in the C57BL/Gr strain. The color of Myo5a^d-l homozygotes is identical to that of Myo5a^d homozygotes, but dilute-lethal mice develop a severe neuromuscular disorder characterized by convulsions and opisthotonus (arching upward of the head and tail), and they usually die at about 3 weeks of age (J:12978).

References

• Original: J:24768 Searle AG, New mutant, allele of Maltese dilution, d. Mouse News Lett. 1951;4:10
• All: 21 reference(s)