Lepr^db-ad
Spontaneous Allele Detail

Summary

• Symbol: Lepr^db-ad
• Name: leptin receptor; adipose
• MGI ID: MGI:1856011
• Gene: Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
• Alliance: Lepr^db-ad page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Undefined
• Mutation details: This allele arose spontaneously in a stock selected for large body size derived from a cross between the Goodale and MacArthur Large selected populations. It was shown to be allelic to Lepr^db. (J:27525)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lepr Mutation: 122 strains or lines available

Notes

Lepr^db-ad, adipose, recessive. This allele arose spontaneously in a stock selected for large body size derived from a cross between the Goodale and MacArthur Large selected populations (J:31691). It was shown to be allelic to Lepr^db (J:27525). Like other mutations at the Lepr locus, homozygotes for adipose show a phenotype very similar to that of Lepr^db homozygotes, differences being no greater than might be caused by differences in genetic background.

References

• Original: J:31691 Falconer DS, et al., Adipose, a new inherited obesity of the mouse. J Hered. 1959;50(6):290-292
• All: 2 reference(s)