Tbx15^de-H
Spontaneous Allele Detail

Summary

• Symbol: Tbx15^de-H
• Name: T-box 15; droopy ear Harwell
• MGI ID: MGI:1856015
• Synonyms: Tbx14, Tbx8
• Gene: Tbx15 Location: Chr3:99147697-99261575 bp, + strand Genetic Position: Chr3, 43.03 cM
• Alliance: Tbx15^de-H page

Pigmentation phenotype of the Tbx15^de-H/Tbx15^de-H a^e/a^e mouse

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: By comparing the sequence of a 1.3kb junction fragment amplified from a homozygous mutant to a public genome sequence, this allele was found to comprise a 216 kb deletion that extends from intron 1 to 148 kb downstream of the polyadenylation sequence, removing all but the first exon of the Tbx15 gene.
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx15 Mutation: 46 strains or lines available

References

• Original: J:233 Curry GA, Genetical and development studies on droopy-eared mice. J Embryol Exp Morphol. 1959 Mar;7(1):39-65
• All: 3 reference(s)