Edar^dl-J
Spontaneous Allele Detail

Summary

• Symbol: Edar^dl-J
• Name: ectodysplasin-A receptor; downless Jackson
• MGI ID: MGI:1856018
• Synonyms: Edar^dlJ
• Gene: Edar Location: Chr10:58436611-58511476 bp, - strand Genetic Position: Chr10, 29.37 cM, cytoband B3
• Alliance: Edar^dl-J page

Mutation origin

• Strain of Origin: STOCK Pmel^si

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele involves a G-to-A transition mutation at coding nucleotide 1135 that causes a glutamate to lysine change at position 379 (p.E379K). (J:56496)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:

6 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Edar Mutation: 30 strains or lines available

Notes

Similar phenotypes have also been described in mice for the Tabby allelic series at the Eda locus.

References

• Original: J:5859 Green MC, et al., Evidence from chimaeras for the pattern of proliferation of epidermis in the mouse. Genet Res. 1977 Jun;29(3):279-84
• All: 22 reference(s)