Frl^b
Radiation induced Allele Detail

Summary

• Symbol: Frl^b
• Name: furloss; furloss b
• MGI ID: MGI:1856033
• Gene: Frl Location: unknown
• Alliance: Frl^b page

Mutation origin

• Strain of Origin: (101 x C3H)F1

Mutation description

• Allele Type: Radiation induced
• Inheritance: Dominant

Phenotypes

Key:

hm	homozygous	ht	heterozygous	tg	involves transgenes	√	phenotype observed
cn	conditional genotype	cx	complex: > 1 genome feature	ot	other: hemizygous, indeterminate,...	N	normal phenotype

Genotype/
Background:

	Allelic Composition	Genetic Background	Cell Line(s)
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hm1	Frl^b/Frl^b	Not Specified
ht2	Frl^b/Frl^+	Not Specified

Phenotypes:

Affected Systems	hm1	ht2
show or hide all annotated terms
growth/size/body		√
decreased birth body size		√
decreased body weight		√
integument	√	√
abnormal coat appearance	√
abnormal hair growth	√
focal hair loss		√
progressive hair loss		√
sparse hair		√
striated fur		√
abnormal hair shedding		√
wrinkled skin		√
mortality/aging	√
decreased survivor rate	√
prenatal lethality, incomplete penetrance	√

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Frl Mutation: 4 strains or lines available

References

• Original: J:7103 Stelzner KF, Four dominant autosomal mutations affecting skin and hair development in the mouse. J Hered. 1983 May-Jun;74(3):193-6
• All: 1 reference(s)