Sgk3^fz
Spontaneous Allele Detail

Summary

• Symbol: Sgk3^fz
• Name: serum/glucocorticoid regulated kinase 3; fuzzy
• MGI ID: MGI:1856038
• Gene: Sgk3 Location: Chr1:9868332-9971070 bp, + strand Genetic Position: Chr1, 2.08 cM
• Alliance: Sgk3^fz page

Mutation origin

• Strain of Origin: CFW stock

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: This mutation comprises insertion of a single adenine following nucleotide 579 of the cDNA sequence, in a region encoded by exon 10 of the gene, that causes a shift in the amino acid reading frame and premature termination of protein translation following leucine 192 (Leu192Ter), which resides in the serine/threonine kinase domain. (J:125551)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Sgk3 Mutation: 30 strains or lines available

References

• Original: J:90 DICKIE MM, et al., Fuzzy mice. J Hered. 1950 Jul;41(7):193-6
• All: 10 reference(s)