Lbr^ic
Spontaneous Allele Detail

Summary

• Symbol: Lbr^ic
• Name: lamin B receptor; ichthyosis
• MGI ID: MGI:1856063
• Synonyms: ic
• Gene: Lbr Location: Chr1:181642880-181669933 bp, - strand Genetic Position: Chr1, 84.89 cM
• Alliance: Lbr^ic page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous mutation that arose in a sib-mated stock at Edinburgh in 1948. The mutation in the ic mouse was identified as a transition (523C>T) that introduces a premature stop codon at the glutamine codon at position 175 (p.Q175*).
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Lbr^ic

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbr Mutation: 57 strains or lines available

References

• Original: J:64274 Carter TC, et al., ic - ichthyosis. Mouse News Lett. 1949;1S:1
• All: 14 reference(s)