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Mgrn1md-2J
Spontaneous Allele Detail
Summary
Symbol: Mgrn1md-2J
Name: mahogunin, ring finger 1; mahoganoid 2 Jackson
MGI ID: MGI:1856072
Synonyms: md2J
Gene: Mgrn1  Location: Chr16:4704113-4756160 bp, + strand  Genetic Position: Chr16, 2.48 cM, cytoband A1
Alliance: Mgrn1md-2J page
Mutation
origin
Strain of Origin:  C3H/HeJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Transposon insertion
 
Mutation detailsThe mutation in md2J has been attributed to an 8 kb retroviral insertion within exon 12. Northern analysis and RT-PCR indicate that the expression of transcript is greatly reduced in these mice. (J:80182)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 42 assay results
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgrn1 Mutation:  55 strains or lines available
Notes
Genbank ID for this allele: AF532997, AF532998
References
Original:  J:30778 Sweet HO, et al., Remutations at The Jackson Laboratory (Update to Mouse Genome 1993; 91:862-5 - J16313). Mouse Genome. 1995;93(4):1030-4
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory