Ap3d1^mh
Spontaneous Allele Detail

Summary

• Symbol: Ap3d1^mh
• Name: adaptor-related protein complex 3, delta 1 subunit; mocha
• MGI ID: MGI:1856083
• Synonyms: mh, mocha
• Gene: Ap3d1 Location: Chr10:80542790-80578098 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Ap3d1^mh page

Mutation origin

• Strain of Origin: B6.C3-Grxcr1^pi

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The mutation is a 12 kb deletion that removes at least two exons, resulting in a 496 bp deletion of coding material shortly after the initiating ATG codon and causing an out of frame translation followed by a premature termination site. (J:50662)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ap3d1 Mutation: 79 strains or lines available

References

• Original: J:5511 Lane PW, et al., Mocha, a new coat color and behavior mutation on chromosome 10 of the mouse. J Hered. 1974 Nov-Dec;65(6):362-4
• All: 35 reference(s)