Ap3d1^mh-2J
Spontaneous Allele Detail

Summary

• Symbol: Ap3d1^mh-2J
• Name: adaptor-related protein complex 3, delta 1 subunit; mocha 2 Jackson
• MGI ID: MGI:1856084
• Synonyms: mh^2J
• Gene: Ap3d1 Location: Chr10:80542790-80578098 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Ap3d1^mh-2J page

Ap3d1^mh-2J/Ap3d1^mh-2J coat color dilution is attenuated in Ap3d1^mh-2J/Ap3d1^mh-2J Nxf1^Mvb1/Nxf1^Mvb1 mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C3H/HeJ

Mutation description

Allele Type: Spontaneous (Hypomorph) Mutation: Transposon insertion Mutation details: The mutation was identified as a viral-like, intracisternal A particle (IAP) insertion at an intron exon boundary. The mutation results in a C-terminally truncated protein. Both low levels of normal and larger amounts of the mutant transcript are present in this hypomorphic allele. (J:82264) Inheritance: Recessive

Schematic of the location of the IAP insertion generating the Ap3d1^mh-2J allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ap3d1 Mutation: 79 strains or lines available

Notes

Genbank ID for this allele: AF469668, AF469669, AF469670, AF469671, AH012500

References

• Original: J:59842 Miller CL, et al., Hippocampal auditory gating in the hyperactive mocha mouse. Neurosci Lett. 1999 Nov 26;276(1):57-60
• All: 7 reference(s)