Mitf^mi-bw
Spontaneous Allele Detail

Summary

• Symbol: Mitf^mi-bw
• Name: melanogenesis associated transcription factor; black eyed white
• MGI ID: MGI:1856089
• Gene: Mitf Location: Chr6:97784013-97998310 bp, + strand Genetic Position: Chr6, 45.05 cM
• Alliance: Mitf^mi-bw page

Mutation origin

• Strain of Origin: C3H

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: This allele comprises a 7.2 kb novel L1 element insertion into intron sequences located between exons 3 and 4. This insertion reduces the amount of mRNAs for two splicing isoforms of this gene and abolishes expression of a third isoform. (J:56633)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Mitf Mutation: 74 strains or lines available

References

• Original: J:13071 Kreitner PC, Linkage studies in a new black-eyed white mutation in the house mouse (not W). J Hered. 1957;48(6):300-304
• All: 14 reference(s)