Mitf^mi-rw
Spontaneous Allele Detail

Summary

• Symbol: Mitf^mi-rw
• Name: melanogenesis associated transcription factor; red eyed white
• MGI ID: MGI:1856091
• Gene: Mitf Location: Chr6:97784013-97998310 bp, + strand Genetic Position: Chr6, 45.05 cM
• Alliance: Mitf^mi-rw page

Mutation origin

• Strain of Origin: CBA/J

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: This allele contains a large genomic deletion that begins approximately 6kb upstream of the melanocyte-specific 5' end and includes the heart-specific 5'end encompassing exons 1H,1D and 1B. (J:21366, J:132153)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Mitf Mutation: 74 strains or lines available

Notes

Mitf^mi-rw/Mitf^mi mice are all white with small or absent eyes; Mitf^mi-rw/Mitf^mi-sp, fully pigmented except for a white belly spot; and Mitf^mi-rw/Mitf^Mi-wh mostly white with tan spots and red eyes (J:13661).

References

• Original: J:13661 Southard JL, Red-eyed white (mi^rw). Mouse News Lett. 1974;51:23
• All: 6 reference(s)