Vsx2^or-J
Spontaneous Allele Detail

Summary

• Symbol: Vsx2^or-J
• Name: visual system homeobox 2; ocular retardation Jackson
• MGI ID: MGI:1856112
• Synonyms: Chx10^-, orJ
• Gene: Vsx2 Location: Chr12:84616602-84642231 bp, + strand Genetic Position: Chr12, 39.28 cM
• Alliance: Vsx2^or-J page

Vsx2^or-J/Vsx2^or-J and control

Show the 7 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl^Sl

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: The molecular mutation is a premature stop codon in exon 3, corresponding to the homeobox domain of the encoded protein. (J:30800, J:32083)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	183 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vsx2 Mutation: 23 strains or lines available

References

• Original: J:5767 Theiler K, et al., A new allele of ocular retardation: early development and morphogenetic cell death. Anat Embryol (Berl). 1976 Dec 22;150(1):85-97
• All: 39 reference(s)