Pax6^Sey
Spontaneous Allele Detail

Summary

• Symbol: Pax6^Sey
• Name: paired box 6; small eye
• MGI ID: MGI:1856155
• Synonyms: P5, Pax6-, Pax6^SeyEd, sey
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^Sey page

Development of the Pax6^Sey/Pax6⁺ lens

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: Line selected for low body weight

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-T transversion in coding nucleotide 622 (NM_001244198.2) changes the glycine codon at position 208 to a stop codon (Gly208*; NP_001231127.1), resulting in premature termination before the homeobox domain. (J:2301)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:	873 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	36 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 8 strains available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 94 strains or lines available

References

• Original: J:12101 Roberts RC, Small-eyes, a new dominant mutant in the mouse. Genet Res. 1967;9(1):121-122
• All: 177 reference(s)