Pax6^Sey-H
Radiation induced Allele Detail

Summary

• Symbol: Pax6^Sey-H
• Name: paired box 6; small eye, Harwell
• MGI ID: MGI:1856156
• Synonyms: Sey^MH
• Gene: Pax6 Location: Chr2:105499245-105527709 bp, + strand Genetic Position: Chr2, 55.31 cM
• Alliance: Pax6^Sey-H page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Deletion
• Pax6^Sey-H involves 1 genes/genome features (Pax6) View all
• Mutation details: Mutation is a large deletion including the Pax6 gene. Breakpoints are not precisely mapped, but the deletion is likely to include the neighboring Wilm's tumor (Wt1) gene. (J:2301, J:139665)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pax6 Mutation: 94 strains or lines available

References

• Original: J:8534 Hogan BL, et al., Small eyes (Sey): a homozygous lethal mutation on chromosome 2 which affects the differentiation of both lens and nasal placodes in the mouse. J Embryol Exp Morphol. 1986 Sep;97(1):95-110
• All: 4 reference(s)