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KitlSl-pan
Radiation induced Allele Detail
Summary
Symbol: KitlSl-pan
Name: kit ligand; steel panda
MGI ID: MGI:1856167
Synonyms: KL, Mgf, Sl11H, Slpan
Gene: Kitl  Location: Chr10:99851492-99936278 bp, + strand  Genetic Position: Chr10, 51.4 cM
Alliance: KitlSl-pan page
KitlSl-pan/KitlSl-pan

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Mutation
description
Allele Type:    Radiation induced
Mutation:    Inversion
  KitlSl-pan involves 1 genes/genome features (Kitl) View all
 
Mutation detailsKaryotypic analysis revealed an ~40 cM paracentric inversion with the proximal breakpoint at the junction of bands 10B1/10B2 and the distal break at the junction of bands 10C2/10C3. The inversion is 115 kb 5' of the Kitl coding sequence. Northern analysis shows normal transcript size but this allele exerts tissue-specific reduction in Kitl mRNA expression. (J:23593)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kitl Mutation:  94 strains or lines available
References
Original:  J:14014 Beechey CV, et al., Male-fertile black-eyed white at Sl locus. Mouse News Lett. 1985;73:17
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory