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Th
Spontaneous Allele Detail
Summary
Symbol: Th
Name: brachyury, T-box transcription factor T; T-Harwell
MGI ID: MGI:1856186
Gene: T  Location: Chr17:8653255-8661328 bp, + strand  Genetic Position: Chr17, 4.92 cM
Alliance: Th page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Spontaneous
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any T Mutation:  59 strains or lines available
Notes
Th, T-Harwell, semidominant. Found in the control series of an irradiation experiment. T/+ mice are indistinguishable from T/+, but Th/Th mice die at an earlier stage than T/T, being already highly abnormal at 8 days (J:13072).
References
Original:  J:13072 Lyon MF, A new dominant T-allele in the house mouse. J Hered. 1959;50(3):140-142
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory