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Tc-2H
Chemically and radiation induced Allele Detail
Summary
Symbol: Tc-2H
Name: brachyury, T-box transcription factor T; curtailed 2 Harwell
MGI ID: MGI:1856193
Gene: T  Location: Chr17:8653255-8661328 bp, + strand  Genetic Position: Chr17, 4.92 cM
Alliance: Tc-2H page
Mutation
origin
Strain of Origin:  (C3H/HeH x 101/H)F1
Mutation
description
Allele Type:    Chemically and radiation induced
Mutation:    Single point mutation
 
Mutation detailsSequencing genomic DNA from the open reading frame revealed a C to A transversion that would result in a protein truncated at the carboxyl-terminal end. (J:85398)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any T Mutation:  59 strains or lines available
References
Original:  J:85396 Cattanach BM, et al., A new curtailed mutation. Mouse News Lett. 1987;77:122
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory