Summary | ||||||||||||||
Mutation origin |
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Mutation description |
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Phenotypes |
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View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Find Mice (IMSR) |
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Notes |
EdaTa-25H. A female with the typical tabby phenotype resulted from 6 Gy spermatogonial irradiation. She produced EdaTa-25H/+, +/+, and hemizygous EdaTa-25H daughters, but only hemizygous +/Y males. The EdaTa-25H hemizygous daughters were chromosomally XY, and, rather than ovaries, had abdominally located testes. This indicated a deletion of both the Eda and Ar loci, which was given the symbol EdaTa-25H as an allele at the tabby locus. There is a shortage of both heterozygous and hemizygous EdaTa-25H mice, and EdaTa-25H/+ heterozygous females tend to have smaller litters than their wild-type sibs. Heterozygotes (but not hemizygotes) often show skeletal defects (J:14235).
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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