Pax1^un
Spontaneous Allele Detail

Summary

• Symbol: Pax1^un
• Name: paired box 1; undulated
• MGI ID: MGI:1856222
• Synonyms: un
• Gene: Pax1 Location: Chr2:147203850-147216972 bp, + strand Genetic Position: Chr2, 72.63 cM
• Alliance: Pax1^un page

Mutation origin

• Strain of Origin: fancier's mice

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: A point mutation results in a substitution of glycine for serine at position 15 of the paired box motifand markedly decreases the DNA-binding ability of the Pax1 protein and changes its DNA specificity. (J:9424)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Pax1 Mutation: 28 strains or lines available

References

• Original: J:314 Wright ME, Undulated: a new genetic factor in Mus musculus affecting the spine and tail. Heredity. 1947;1(1):137-41
• All: 15 reference(s)