Kit^W-55J
Spontaneous Allele Detail

Summary

• Symbol: Kit^W-55J
• Name: KIT proto-oncogene receptor tyrosine kinase; dominant spotting 55 Jackson
• MGI ID: MGI:1856251
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^W-55J page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Nucleotide sequence analysis revealed that a C-to-T point mutation results in the substitution of threonine with methionine at position 660 (p.T660M), which is within the ATP-binding domain. (J:28221)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 182 strains or lines available

References

• Original: J:16313 Sweet HO, Remutations at The Jackson Laboratory. Mouse Genome. 1993;91(4):862-65
• All: 3 reference(s)