Tgm3^we
Spontaneous Allele Detail

Summary

• Symbol: Tgm3^we
• Name: transglutaminase 3, E polypeptide; wellhaarig
• MGI ID: MGI:1856269
• Gene: Tgm3 Location: Chr2:129854269-129892319 bp, + strand Genetic Position: Chr2, 63.19 cM
• Alliance: Tgm3^we page

Mutation origin

• Strain of Origin: Agnes Bluhm's stocks

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A spontaneous C-to-T point mutation in exon 13 results in premature termination codon at arginine 658 (p.R658*) and the loss of the last 36 amino acids. There is also an insertion/duplication of AGTC in intron 12 between position chr2:130048178-130048179 (GRCm38) (duplication of 130048179-130048182). (J:225940)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 6 strains available Cell Lines: 0 lines available
• Carrying any Tgm3 Mutation: 55 strains or lines available

References

• Original: J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
• All: 11 reference(s)