Atp8a2^wl-vmd
Spontaneous Allele Detail

Summary

• Symbol: Atp8a2^wl-vmd
• Name: ATPase, aminophospholipid transporter-like, class I, type 8A, member 2; wabbler lethal vestibulomotor degeneration
• MGI ID: MGI:1856273
• Synonyms: vmd
• Gene: Atp8a2 Location: Chr14:59884980-60324363 bp, - strand Genetic Position: Chr14, 31.49 cM
• Alliance: Atp8a2^wl-vmd page

Mutation origin

• Strain of Origin: C3H/HeSnJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: A 9167 bp deletion removes exon 32. This results in a 32 amino acid deletion in the ninth transmembrane domain. (J:188127, J:222308)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atp8a2 Mutation: 74 strains or lines available

References

• Original: J:11718 Bronson RT, et al., Genetic and age related models of neurodegeneration in mice: dystrophic axons. J Neurogenet. 1992 May;8(2):71-83
• All: 6 reference(s)