Gli3^Xt
Spontaneous Allele Detail

Summary

• Symbol: Gli3^Xt
• Name: GLI-Kruppel family member GLI3; extra toes
• MGI ID: MGI:1856275
• Synonyms: Gli3^-, Xt^H
• Gene: Gli3 Location: Chr13:15638308-15904611 bp, + strand Genetic Position: Chr13, 5.43 cM, cytoband A2
• Alliance: Gli3^Xt page

Mutation origin

• Strain of Origin: CBA/H x (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Spontaneous
• Mutation: Deletion
• Gli3^Xt involves 1 genes/genome features (Gli3) View all
• Mutation details: Southern Blot analysis of genomic DNA from +/+, Xt/+ and Xt/Xt mice showed that at least part of the Gli3 gene (cDNA homologous with a 5' part of the human GLI3 gene) is deleted in the Gli3^Xt allele. (J:1718, J:3333, J:11318)
• Inheritance: Semidominant

Expression

In Mice Carrying this Mutation:

235 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gli3 Mutation: 81 strains or lines available

References

• Original: J:12947 Lyon MF, et al., The overall rates of dominant and recessive lethal and visible mutation induced by spermatogonial X-irradiation of mice. Genet Res. 1964;5(3):448-467
• All: 54 reference(s)