Tyr^c-Bc3
Spontaneous Allele Detail

Summary

• Symbol: Tyr^c-Bc3
• Name: tyrosinase; albino 3 British Columbia
• MGI ID: MGI:1856303
• Synonyms: c^3Bc
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^c-Bc3 page

Mutation origin

• Strain of Origin: SELH/Bc

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: Sequence analysis showed that Tyr^c-Bc3 is defined by an insertion of a 5542 bp sequence from an early transposon into exon 1. Northern blot analysis with a mouse tyrosinase cDNA probe showed no detectable transcripts in mice homozygous for this allele. (J:49845)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 379 strains or lines available

References

• Original: J:18053 Juriloff DM, et al., Three spontaneous mutations at the albino locus in SELH/Bc mice. Genome. 1994 Apr;37(2):190-7
• All: 3 reference(s)