Tyr^c-44H
Chemically and radiation induced Allele Detail

Summary

• Symbol: Tyr^c-44H
• Name: tyrosinase; albino 44 Harwell
• MGI ID: MGI:1856307
• Synonyms: c^44H, dark-eyed albino
• Gene: Tyr Location: Chr7:87073979-87142637 bp, - strand Genetic Position: Chr7, 49.01 cM
• Alliance: Tyr^c-44H page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Chemically and radiation induced
• Mutation: Single point mutation
• Mutation details: The defect is a G-to-T point mutation, altering serine to isoleucine at position 146 or 128 (p.S146I in pre-protein, p.S128I in mature protein) in the encoded protein. (J:18620)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tyr Mutation: 379 strains or lines available

References

• Original: J:12721 Cattanach BM, et al., Dark-eyed albinism, c^44H. Mouse News Lett. 1988;81:64
• All: 4 reference(s)