Atp7a^Mo-11H
Chemically and radiation induced Allele Detail

Summary

• Symbol: Atp7a^Mo-11H
• Name: ATPase, copper transporting, alpha polypeptide; mottled 11 Harwell
• MGI ID: MGI:1856323
• Synonyms: Atp7a^mo11H
• Gene: Atp7a Location: ChrX:105070882-105168532 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Atp7a^Mo-11H page

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Chemically and radiation induced
• Mutation: Single point mutation
• Mutation details: This mutation arose in mutagenesis studies at Harwell. Molecular analysis detected a C to A transversion mutation at position 4173 that alters codon 1364 from alanine to aspartate. (J:38977)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp7a Mutation: 69 strains or lines available

Notes

The mutation was derived from a mutagenized male that had been treated with both hydroxyurea and X-rays.

References

• Original: J:16303 Rasberry C, et al., Three new mottled mutations - Mo^10H, Mo^11H, and Mo^12H. Mouse Genome. 1993;91(4):851-53
• All: 3 reference(s)