Glra1^spd
Spontaneous Allele Detail

Summary

• Symbol: Glra1^spd
• Name: glycine receptor, alpha 1 subunit; spasmodic
• MGI ID: MGI:1856362
• Synonyms: Glra1^{spd -}, spd
• Gene: Glra1 Location: Chr11:55405065-55499024 bp, - strand Genetic Position: Chr11, 33.12 cM
• Alliance: Glra1^spd page

Mutation origin

• Strain of Origin: A/HeJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele is the result of a missense mutation comprising a G-toT transversion producing an alanine-to-serine substitution at position 80 in the N-terminal domain of the encoded protein (p.A80S). (J:18524, J:20373)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Glra1 Mutation: 30 strains or lines available

References

• Original: J:9027 Lane PW, et al., Spasmodic, a mutation on chromosome 11 in the mouse. J Hered. 1987 Nov-Dec;78(6):353-6
• All: 16 reference(s)