Dct^slt
Spontaneous Allele Detail

Summary

• Symbol: Dct^slt
• Name: dopachrome tautomerase; slaty
• MGI ID: MGI:1856379
• Synonyms: slt
• Gene: Dct Location: Chr14:118250202-118289656 bp, - strand Genetic Position: Chr14, 61.6 cM
• Alliance: Dct^slt page

Mutation origin

• Strain of Origin: STOCK Grem1^ld-J Atrn^mg

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: Sequence analysis showed this allele involves a G-to-A transition (C-to-T on forward strand) at coding nucleotide 581 which results in a arginine to glutamine missense mutation at position 194 (p.R194Q). The mutation reduces but does not eliminate enzyme activity. (J:1961)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Dct Mutation: 35 strains or lines available

References

• Original: J:13534 Green MC, Slaty (slt). Mouse News Lett. 1972;47:36
• All: 12 reference(s)