Reln^rl
Spontaneous Allele Detail

Summary

• Symbol: Reln^rl
• Name: reelin; reeler
• MGI ID: MGI:1856398
• Synonyms: rl, rl-, rl^J, rln^rl
• Gene: Reln Location: Chr5:22089452-22549700 bp, - strand Genetic Position: Chr5, 9.98 cM, cytoband A3-B1
• Alliance: Reln^rl page

The Reln^rl/Reln^rl mouse

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: "snowy-bellied" stock or unspecified inbred strain

Mutation description

• Allele Type: Spontaneous
• Mutation: Intergenic deletion
• Mutation details: This allele comprises an apprxomately 126.7 kb deletion that has a breakpoint in an intron of reelin and removes coding sequence downstream of cDNA nucleotide 3619. No reelin mRNA is detected in homozygotes. (J:24458, J:24459)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	224 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Reln Mutation: 209 strains or lines available

Notes

Early studies were summarized and critically reviewed by Goffinet (J:12281).

References

• Original: J:13038 Falconer DS, Two new mutants, "trembler" and "reeler," with neurological actions in the house mouse. J Genet. 1951;50(2):192-201
• All: 287 reference(s)