Reln^rl-tg
Transgenic Allele Detail

Summary

• Symbol: Reln^rl-tg
• Name: reelin; reeler tg
• MGI ID: MGI:1856417
• Gene: Reln Location: Chr5:22089452-22549700 bp, - strand Genetic Position: Chr5, 9.98 cM, cytoband A3-B1
• Alliance: Reln^rl-tg page

Transgene origin

• Strain of Origin: (B6C3F1 x B6D2F1)

Transgene description

• Transgene Type: Transgenic
• Mutation: Insertion
• Mutation details: Southern blot analysis of genomic DNA showed that this allele was the result of the integration of a mutated c-fos transgene into the Reln locus with no gross structural rearrangements. Complementation analysis of offspring from a mating of mice hemizygous for the transgene and heterozygous for Reln^rl showed 25% of the offspring had a reeler phenotype. (J:21534)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reln Mutation: 209 strains or lines available

References

• Original: J:21534 Miao GG, et al., Isolation of an allele of reeler by insertional mutagenesis. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):11050-4
• All: 4 reference(s)