Mafb^kr
Radiation induced Allele Detail

Summary

• Symbol: Mafb^kr
• Name: MAF bZIP transcription factor B; kreisler
• MGI ID: MGI:1856419
• Synonyms: Krml^kr, Mafb^Krml-kr
• Gene: Mafb Location: Chr2:160205623-160208985 bp, - strand Genetic Position: Chr2, 80.92 cM
• Alliance: Mafb^kr page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Radiation induced
• Mutation: Inversion
• Mutation details: There is a chromosomal inversion approximately 0.8 +/- 0.8cM in length very near the Mafb gene. The protein product of the normal gene is a transcription factor. The effect of the inversion appears to be to abolish transcription from the Mafb gene, not by physical disruption of the transcribed sequence, but by separation of coding sequences from a putative regulatory element or introduction of an inhibitory element. (J:4596, J:22020, J:83936)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	167 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Mafb Mutation: 20 strains or lines available

References

• Original: J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
• All: 19 reference(s)