Dst^Tg4
Transgenic Allele Detail

Summary

• Symbol: Dst^Tg4
• Name: dystonin; transgene insertion 4
• MGI ID: MGI:1856421
• Synonyms: bullous pemphigoid antigen 1, 230kD, Dst^Bpag1, dtTG4, Tg4
• Gene: Dst Location: Chr1:33947306-34347742 bp, + strand Genetic Position: Chr1, 12.91 cM
• Alliance: Dst^Tg4 page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Modified isoform(s))
• Mutations: Insertion, Intragenic deletion
• Mutation details: Approximately 15 copies of an Hsp68-lacZ transgene inserted into the genome, accompanied by a 45 kb deletion that removed the exons containing sequences for neural-specific alternative isoforms of the encoded protein. (J:17630, J:26733)
• Inheritance: Not Specified

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dst Mutation: 557 strains or lines available

References

• Original: J:17844 Kothary R, et al., A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature. 1988 Sep 29;335(6189):435-7
• All: 23 reference(s)