a^5mnu
Chemically induced Allele Detail

Summary

• Symbol: a^5mnu
• Name: nonagouti; nonagouti 5methylnitrosourea
• MGI ID: MGI:1856427
• Gene: a Location: Chr2:154792519-154892932 bp, + strand Genetic Position: Chr2, 76.83 cM
• Alliance: a^5mnu page

Mutation origin

• Strain of Origin: (101/H x C3H/HeH)F1

Mutation description

• Allele Type: Chemically induced (other)
• Mutation: Intragenic deletion
• Mutation details: This allele comprises a 2.8 kb deletion. The deletion includes 129 bp that also are deleted from the distal breakpoint of the allele a^{jIs(17;In2)1Gso}. In neonatal skin a transcript is present at wild-type levels, but is decreased in size to an extent that is consistent with a deletion of the third exon of nonagouti. (J:3523, J:16567)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any a Mutation: 463 strains or lines available

Notes

This allele was induced by methylnitrosourea (MNU) in spermatogonia. Homozygotes are jet black in color (J:16567).

References

• Original: J:16567 Bultman SJ, et al., Molecular characterization of a region of DNA associated with mutations at the agouti locus in the mouse. Proc Natl Acad Sci U S A. 1991 Sep 15;88(18):8062-6
• All: 2 reference(s)