Hr^rh-8J
Spontaneous Allele Detail

Summary

• Symbol: Hr^rh-8J
• Name: lysine demethylase and nuclear receptor corepressor; rhino 8 Jackson
• MGI ID: MGI:1856506
• Gene: Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
• Alliance: Hr^rh-8J page

Mutation origin

• Strain of Origin: B10.D2-H2^d/nSnJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: Molecular analysis revealed that a GA-to-TT substitution at positions 1910 and 1911 had occurred. This is predicted to result in a glutamine to histidine amino acid substitution at position 511 and a lysine to stop codon subsitution at position 512. (J:50909)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hr Mutation: 87 strains or lines available

References

• Original: J:30778 Sweet HO, et al., Remutations at The Jackson Laboratory (Update to Mouse Genome 1993; 91:862-5 - J16313). Mouse Genome. 1995;93(4):1030-4
• All: 2 reference(s)