Kit^W-ei
Spontaneous Allele Detail

Summary

• Symbol: Kit^W-ei
• Name: KIT proto-oncogene receptor tyrosine kinase; Eiche's dominant spotting
• MGI ID: MGI:1856510
• Gene: Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Kit^W-ei page

Mutation origin

• Strain of Origin: C57BL

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele was first defined by a noncomplementation test. There is a G-to-C substitution at coding nucleotide 1790 (transcript NM_021099) which results in the glycine at amino acid position 597 being replaced by alanine (p.G597A). (J:19931, J:28100)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kit Mutation: 182 strains or lines available

References

• Original: J:28100 Eiche A, et al., Dominant or recessive? Different models of expression of a spontaneous new mutation in the mouse. Hereditas. 1982;97:316-7 (Abstr)
• All: 3 reference(s)