Kcnj6^wv
Spontaneous Allele Detail

Summary

• Symbol: Kcnj6^wv
• Name: potassium inwardly-rectifying channel, subfamily J, member 6; weaver
• MGI ID: MGI:1856525
• Synonyms: wv
• Gene: Kcnj6 Location: Chr16:94549495-94798560 bp, - strand Genetic Position: Chr16, 55.44 cM
• Alliance: Kcnj6^wv page

Kcnj6^wv/Kcnj6^wv

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: A G-to-A transition at coding nucleotide 466 replaces a glycine with serine at amino acid residue 156 (p.G156S), affecting the highly conserved H5 domain of the channel. (J:29230, J:30864)
• Inheritance: Recessive

Expression

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	22 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Kcnj6^wv

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Kcnj6 Mutation: 26 strains or lines available

References

• Original: J:13422 Lane PW, Weaver, wv. Mouse News Lett. 1964;30:32
• All: 208 reference(s)