Mitf^mi-ce
Spontaneous Allele Detail

Summary

• Symbol: Mitf^mi-ce
• Name: melanogenesis associated transcription factor; cloudy-eye
• MGI ID: MGI:1856532
• Synonyms: ce, cloudy eyed, mi^ce, MITF^ce
• Gene: Mitf Location: Chr6:97784013-97998310 bp, + strand Genetic Position: Chr6, 45.05 cM
• Alliance: Mitf^mi-ce page

Mutation origin

• Strain of Origin: DBA/2N

Mutation description

• Allele Type: Spontaneous
• Mutation: Single point mutation
• Mutation details: This allele comprises a C-to-T that introduces a stop codon at arginine codon 370 between the second helix and the leucine zipper domains (NM_001113198.1:c.1108C>T, p.(Arg370*)). (J:21366)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mitf Mutation: 74 strains or lines available

References

• Original: J:34879 Zimring DC, et al., Microphthalmia cloudy-eye (mi(ce)): a new murine allele. J Hered. 1996 Jul-Aug;87(4):334-8
• All: 12 reference(s)